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PCR|One system

makes important information accessible to patients and to healthcare professionals

Our goal is to deliver the immediate detection of multiple genetic targets in a fully automated run using the most reliable, gold-standard PCR technology.

PCR|ONE ideally integrates into the laboratory environment, offering minimum hands-on time, a rapid response to urgent testing needs, and efficient use of bench space.
Rapid molecular diagnostics offered by the PCR|ONE system will effectively help general practitioners and their patients with spot-on diagnosis during a consultation.

Solution

PCR|ONE is the world’s rapid detection of bacteria and viruses system
– up to 20 different pathogens and drug resistance genes

PCR|ONE system is a complete, stand-alone solution for immediate detection of a wide range of pathogens and genetic targets at the point of care. The system consists of analyser and disposable cartridges that are loaded with clinical samples and automatically processed for detailed diagnosis within 15 minutes. PCR|ONE uses physical multiplexing as one of the two systems in the world. This technology allows for fast expansion and adaptation of the assay panels in response to changing needs and epidemiological threats. 

Technology

Technology – simultaneous detection of up to 20 genetic targets within 15 minute turn around time (TAT)

Proprietary infrared (IR) amplification technology
Allows for 40 cycles of real-time PCR in 7 minutes. This patented ultra-fast PCR technology has been tested tens of thousands of times over 8 years of development of the PCR|ONE system.

Microfluidics for physical multiplexing
PCR|ONE conducts each PCR in a separate
micro-well and uses triplicates of each reaction for maximum robustness and accuracy.

Microfluidics for flexibility
Four types of lysis, filtering, and diverse liquid-handling protocols for lysis, isolation, and purification of genetic material.

16-well geometry
32-well geometry
64-well geometry

Advantages

Ease of use enables placement in a variety of clinically - relevant locations, from Point - of - Care to centralized laboratory

Availability of results in 15 minutes. In all clinical scenarios critical results can be delivered when needed; rapid test results allow for optimization of the patient journey

PCR|ONE offers a unique combination of ease and speed of testing with high multiplexing capability:

15 minute TTR

up to 20 targets

sample in – answer out

easy to use

fully automated analysis

price competitive

physical multiplexing (easy to modify or add new reactions)

fast adaptation to mutations

We have designed and developed PCR|ONE to be an “information generator” to deliver actionable test results for clinicians in a timely and efficient manner in a variety of care settings. Offering complete required information:

  • at the point of need
  • in the time clinicians require

Hospital admission wards.

The PCR|ONE system is ideally suited for use in hospital admission wards for systematic and immediate screening of patients. The PCR|ONE system meets key needs: economic efficiency, rapid screening, and rapid adaptation to the changing landscape of the genetic variants of pathogens.

Laboratories

The unique speed and simplicity of use of the PCR|ONE system provide the shortest time to results as well as gold-standard confidence in results. PCR|ONE test panels are executed within 15 minutes with only ~1 minute of hands-on time. A single PCR|ONE system can test up to 30 samples within an 8-hour shift. This high bench-space and cost efficiency means that this system is ideal for integrating into the laboratory environment.

Doctor’s office/ ICU Acute Care

Immediate molecular diagnostics should be available right at the doctor’s office, where patients seek immediate—and informed—help. Many common conditions such as influenza require simultaneous tests against multiple genetic targets. The PCR|ONE platform delivers this capacity in point-of-care format

Airport

Ease of use enables placement of PCR|ONE in a variety of clinically relevant locations, from Point-of-Care and centralized laboratory to airports, drive through stations and any other public places relevant during the spread of pandemics. We can test the high-risk suspect patients selected by a less specific method (e.g.temperature measurement). This reduces costs (by eliminating the isolation of actually negative – i.e. noninfected people), and isolating infected people in an instant.

Retail Points/Pharmaceries

Non-traditional use scenarios gained momentum, including point-of-care (POC) Dx at pharmacy and retail settings. PCR|ONE fits this trend well thanks to the physical multiplexing that allows offering a wide range of tests and their rapid adaptation, and the ease of use allows it to be located outside the hospital or laboratory.

Nursing home

PCR|ONE allows for non-laboratory workers to perform tests on-site in a plug-and-play mode,  so all entrants can be tested to minimise the risk of infection of the most vulnerable elderly people. Moreover, the short TTR offered by PCR|ONE further simplifies the logistics, and resonable cost of a single test increases accessibility.

  • Hospital
  • Laboratories
  • Doctor’s office/ ICU Acute Care

The PCR|ONE system is ideally suited for use in hospital admission wards for systematic and immediate screening of patients. The PCR|ONE system meets key needs: economic efficiency, rapid screening, and rapid adaptation to the changing landscape of the genetic variants of pathogens.

The unique speed and simplicity of use of the PCR|ONE system provides the shortest time to results as well as gold - standard confidence in results. PCR|ONE test panels are executed within 15 minutes with only ~1 minute of hands - on time. A single PCR|ONE system can test up to 30 samples within an 8-hour shift. This high bench-space and cost efficiency means that this system is ideal for integrating into the laboratory environment.

Immediate molecular diagnostics should be available right at the doctor’s office, where patients seek immediate — and informed — help. Many common conditions such as influenza require simultaneous tests against multiple genetic targets. The PCR|ONE platform delivers this capacity in point-of-care format

  • Airport
  • Retail Points/Pharmaceries
  • Nursing home

Ease of use enables placement of PCR|ONE in a variety of clinically relevant locations, from Point - of - Care and centralized laboratory to airports, drive through stations and any other public places relevant during the spread of pandemics. We can test the high-risk suspect patients selected by a less specific method (e.g.temperature measurement). This reduces costs (by eliminating the isolation of actually negative - i.e. noninfected people), and isolating infected people in an instant.

Non-traditional use scenarios gained momentum, including point - of - care (POC) Dx at pharmacy and retail settings. PCR|ONE fits this trend well thanks to the physical multiplexing that allows offering a wide range of tests and their rapid adaptation, and the ease of use allows it to be located outside the hospital or laboratory.

PCR|ONE allows for non-laboratory workers to perform tests on-site in a plug - and - play mode,  so all entrants can be tested to minimise the risk of infection of the most vulnerable elderly people. Moreover, the short TTR offered by PCR|ONE further simplifies the logistics, and resonable cost of a single test increases accessibility.

Easy to use

Fast result & Wealth of information

Products

The system offers a high degree of multiplexing, that allows composing diagnostic panels tailored for various clinical applications. PCR|ONE is a versatile platform for development of user-specific and cost-effective point-of-use panels

The system offers unparalled flexibility and capacity to build simple and highly multiplexed panels.​

Physical multiplexing allows for fast expansion and adaptation of the assay panels in response to changing needs and epidemiological landscape.

The ultra-fast and fully automated workflow is compatible with multiple use sceanarios

SARS-CoV-2

Our key message is: test test test – Tedros Adhanom, the WHO General Director​

MRSA

The fastest and most comprehensive detection and characterization

In the pipeline

Outpatient care setting: respiratory panel and STI pane​

News

About us

Curiosity Diagnostics has been accelerated by the Scope Fluidics Group.

PCR|ONE has been accelerated by the Scope Fluidics Group (www.scopefluidics.com). The Scope Fluidics Group develops technological projects for medical diagnostics and healthcare. The strategic goal of the Group is to generate profits as a result of sales of independently developed technology projects for global manufacturers of medical devices. The Scope Fluidics Group provides developed projects with financing, access to laboratories and workshops, and crucial administrative facilities and services.

Contact

Address:
Duchnicka 3, building 16, entrance A,
01-796 Warsaw, Poland

Phone: +48 22 376 21 14


KRS: 0000417594

NIP: 5272675921

REGON: 146095125

The fastest access to molecular Dx information

15

min

rapid test results

20

genes

targets in a single test

64

PCR

reactions in a single test